Vrije Universiteit Amsterdam and Amsterdam UMC organize a symposium on Animal-Free Innovations in Science that will focus on innovations in animal-free methods including in vitro (cell culture) and in silico (computational) approaches. It will address the unique advantages of utilising human derived cells, including induced Pluripotent Stem cells, organoids and multi-organ chip devices. The goal is to bring together scientists from different disciplines from the University of Amsterdam and Vrije Universiteit Amsterdam in an open and constructive setting to discuss the challenges and advantages in encouraging animal-free innovations in basic and translational research.