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    Animal Free Science > Animal-Free Science News

Animal-Free Science News

  • We don’t want to make mice better but people

    Posted by Jen Hochmuth on December 10, 2019

    The transition away from animal testing is for the time being a predominantly silent revolution, but alternatives based on human tissues and mini-organs offer the prospect of acceleration. “This…

    Opinion article
    Continue reading
  • New online database to improve environmental risk assessment of chemicals and avoid animal testing

    Posted by Jen Hochmuth on November 21, 2019

    The EnviroTox database is an international project, led by the Health and Environmental Sciences Institute and involving the JRC. This public database of ecotoxicological data brings together…

    in silico
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  • Human iPSC-derived heart-on-a-chip technology for early drug discovery and development

    Posted by Jen Hochmuth on November 19, 2019

    A human iPSC-derived heart-on-a-chip technology can directly measure in vivo cardiac performance and it can be used to assess the effects of novel compounds on contractility early in the…

    Drug development, In vitro, Toxicology
    Continue reading
  • EU citizens and industry expect ‘big reduction’ in mandatory animal testing

    Posted by Jen Hochmuth on November 15, 2019

    The European Chemicals Agency (ECHA) and the Joint Research Centre scientists have a key role to play in meeting the demand of EU citizens and industry, who want to…

    EU, Meeting Report
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  • Green MEP Tilly Metz calls for EU action plan on alternatives to animal testing

    Posted by Jen Hochmuth on November 15, 2019

    All initiatives to promote alternatives to animal testing are welcome, but lawmakers should be bolder and impose some mandatory measures as well, Luxembourgish MEP Tilly Metz has said.

    EU, Meeting Report
    Continue reading
  • The potential of organoids and kidney-on-a-chip platforms as better predictive models for drug-induced nephrotoxicity

    Posted by Jen Hochmuth on November 13, 2019

    A new review from scientists at the University of Utrecht considers how the complex nature of the kidney complicates in vitro modeling & suggests where 3D culture & organoid…

    Fundamental Research, Scientific review
    Continue reading
  • Mice brains are too different from humans’ to model neurodevelopmental disorders

    Posted by Jen Hochmuth on November 12, 2019

    Most knowledge about how the development of the cerebellum – the brain area that receives and coordinates sensory information and our physical responses to it – comes…

    Disease, Fundamental Research, Scientific Publication
    Continue reading
  • Human liver-on-a-chip predicts human toxicity better than animal studies

    Posted by Jen Hochmuth on November 8, 2019

    A new organ-on-a-chip system can predict human toxicity that was undetected in animal studies for drugs halted in clinical trials and emphasizes species-specific responses in liver toxicity.

    Scientific Publication, Toxicology
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  • Time to move beyond the 3R principles

    Posted by Jen Hochmuth on November 7, 2019

    This recently published study says the time has now come to prioritise the Replacement of animals used for scientific purposes, over refinement and reduction strategies. The 21st Century has…

    Scientific Publication
    Continue reading
  • Book review: Rigor mortis

    Posted by Jen Hochmuth on November 6, 2019

    Scientific research should not be attached to particular dogmas or paradigms but, on the contrary, change its methods according to the results obtained. In his book “Rigor Mortis”, the…

    Academia, Book Review
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