Systematic review: Performance of preclinical models in predicting drug-induced liver injury in humans

A systematic review found that preclinical studies using animals fail to predict a drug’s potential to cause adverse health effects, despite being mandatory in safety and efficacy…

Non-animal Methods in Science and Regulation – EURL ECVAM status report (2020)

This EURL ECVAM report provides information on the progress being made in the development, validation and regulatory application of non-animal methods, as well as on their use…

Vaccine testing without animal testing?

Dutch, Bilthoven based, Intravacc, a global leader in translational research and development of viral and bacterial vaccines, today announced the publication of a study in Scientific Reports on alternatives…

Smoking robot and lung-on-a-chip to study cigarette smoke-induced lung diseases

Researchers at the Wyss Institute at Harvard University have developed an animal-free science innovation platform by combining a robotic smoking machine with a lung-on-a-chip technology to fully and realistically…

Scientists can bio-print a 3D mini liver in 90 days

Human iPSC-derived heart-on-a-chip technology for early drug discovery and development

A human iPSC-derived heart-on-a-chip technology can directly measure in vivo cardiac performance and it can be used to assess the effects of novel compounds on contractility early in the…

A 3D Model of the Human Blood Brain Barrier

Researchers at Vanderbilt University have developed a functional 3D in vitro blood-brain barrier model constructed from induced pluripotent stem cell (iPSC)-derived human brain microvascular endothelial cells…

Pancreas-on-a-Chip Offers New Possibilities for Cystic Fibrosis Research

Researchers at Cincinnati Children’s Hospital Medical Center have developed a human pancreas-on-a-chip to increase our fundamental understanding of the pancreatic function and to identify possible…