Systematic review: Performance of preclinical models in predicting drug-induced liver injury in humans
A systematic review found that preclinical studies using animals fail to predict a drug’s potential to cause adverse health effects, despite being mandatory in safety and efficacy…
Continue readingThe potential of organoids and kidney-on-a-chip platforms as better predictive models for drug-induced nephrotoxicity
A new review from scientists at the University of Utrecht considers how the complex nature of the kidney complicates in vitro modeling & suggests where 3D culture & organoid…
Continue reading