Animal-free science innovations for better COVID-19 research
A great deal of knowledge about the SARS-CoV-2 virus and the COVID-19 disease is needed quickly. In April this year, the Dutch Ministry of Health, Welfare and Sport…
Continue readingSmoking robot and lung-on-a-chip to study cigarette smoke-induced lung diseases
Researchers at the Wyss Institute at Harvard University have developed an animal-free science innovation platform by combining a robotic smoking machine with a lung-on-a-chip technology to fully and realistically…
Continue readingWe don’t want to make mice better but people
The transition away from animal testing is for the time being a predominantly silent revolution, but alternatives based on human tissues and mini-organs offer the prospect of acceleration. “This…
Continue readingHuman iPSC-derived heart-on-a-chip technology for early drug discovery and development
A human iPSC-derived heart-on-a-chip technology can directly measure in vivo cardiac performance and it can be used to assess the effects of novel compounds on contractility early in the…
Continue readingThe potential of organoids and kidney-on-a-chip platforms as better predictive models for drug-induced nephrotoxicity
A new review from scientists at the University of Utrecht considers how the complex nature of the kidney complicates in vitro modeling & suggests where 3D culture & organoid…
Continue readingHuman liver-on-a-chip predicts human toxicity better than animal studies
A new organ-on-a-chip system can predict human toxicity that was undetected in animal studies for drugs halted in clinical trials and emphasizes species-specific responses in liver toxicity.
Continue readingPancreas-on-a-Chip Offers New Possibilities for Cystic Fibrosis Research
Researchers at Cincinnati Children’s Hospital Medical Center have developed a human pancreas-on-a-chip to increase our fundamental understanding of the pancreatic function and to identify possible…
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